Drostanolone was first synthesized in 1959 by H. J. Ringold, the market launch took place in 1969 as "Drolban" for the treatment of inoperable breast cancer in women. Drostanolone is a synthetic derivative of the physiologically occurring sex hormone dihydrotestosterone. As such, it is one of the androgens, a class of sex hormones. Medicinally, drostanolone was used as an ester of drostanolone propionate.
Due to its strongly androgenic properties, drostanolone is misused by advanced athletes in weight training and bodybuilding as a performance-enhancing preparation, for example to increase the bracing force. It also compresses and hardens the muscles.