Sildenafil is a drug from the group of PDE-5 inhibitors, a group of vascular compounds (vasodilating) substances. He gained great awareness as the active substance of 1998 by the US company Pfizer under the name Viagra on the market on the market for the treatment of erectile dysfunction (erectile disorder) at the man. This effect was randomly discovered as part of the development of Sildenafil as a means of treating hypertension and angina pectoris. Meanwhile, various providers are more than 100 preparations with the active ingredient Sildenafil for the treatment of erectile dysfunction in the trade.
In addition to the potency, Sildenafil has also been approved since 2006 for the treatment of idiopathic pulmonary arterial hypertension and pulmonary hypertension in conjunction with a connective tissue disease.
Sildenafil was the first drug of the active ingredient class of the PDE-5 inhibitors. In colloquially, the name Viagra is sometimes used as a collective term for other medicines of this drug group, for example Tadalafil (Cialis), Vardenafil (Levitra) or Avanafil (Spedra).